diff --git a/packages/extension-base/src/background/handlers/Extension.ts b/packages/extension-base/src/background/handlers/Extension.ts
index ca861e43..9e4cb64f 100644
--- a/packages/extension-base/src/background/handlers/Extension.ts
+++ b/packages/extension-base/src/background/handlers/Extension.ts
@@ -409,14 +409,14 @@ export default class Extension {
     return true;
   }
 
-  private signingApproveSignature ({ id, signature }: RequestSigningApproveSignature): boolean {
+  private signingApproveSignature ({ id, signature, signedTransaction }: RequestSigningApproveSignature): boolean {
     const queued = this.#state.getSignRequest(id);
 
     assert(queued, 'Unable to find request');
 
     const { resolve } = queued;
 
-    resolve({ id, signature });
+    resolve({ id, signature, signedTransaction });
 
     return true;
   }
diff --git a/packages/extension-base/src/background/types.ts b/packages/extension-base/src/background/types.ts
index a0c07547..a1467fa4 100644
--- a/packages/extension-base/src/background/types.ts
+++ b/packages/extension-base/src/background/types.ts
@@ -299,6 +299,7 @@ export interface RequestSigningApprovePassword {
 export interface RequestSigningApproveSignature {
   id: string;
   signature: HexString;
+  signedTransaction?: HexString;
 }
 
 export interface RequestSigningCancel {
@@ -358,6 +359,7 @@ export type TransportResponseMessage<TMessageType extends MessageTypes> =
 export interface ResponseSigning {
   id: string;
   signature: HexString;
+  signedTransaction?: HexString;
 }
 
 export interface ResponseDeriveValidate {
diff --git a/packages/extension-chains/src/bundle.ts b/packages/extension-chains/src/bundle.ts
index 241bd8a5..6c020708 100644
--- a/packages/extension-chains/src/bundle.ts
+++ b/packages/extension-chains/src/bundle.ts
@@ -26,7 +26,7 @@ export function metadataExpand (definition: MetadataDef, isPartial = false): Cha
     return cached;
   }
 
-  const { chain, genesisHash, icon, metaCalls, specVersion, ss58Format, tokenDecimals, tokenSymbol, types, userExtensions } = definition;
+  const { chain, genesisHash, icon, metaCalls, rawMetadata, specVersion, ss58Format, tokenDecimals, tokenSymbol, types, userExtensions } = definition;
   const registry = new TypeRegistry();
 
   if (!isPartial) {
@@ -41,8 +41,8 @@ export function metadataExpand (definition: MetadataDef, isPartial = false): Cha
 
   const hasMetadata = !!metaCalls && !isPartial;
 
-  if (hasMetadata) {
-    registry.setMetadata(new Metadata(registry, base64Decode(metaCalls)), undefined, userExtensions);
+  if (hasMetadata || !!rawMetadata) {
+    registry.setMetadata(new Metadata(registry, hasMetadata ? base64Decode(metaCalls) : rawMetadata), undefined, userExtensions);
   }
 
   const isUnknown = genesisHash === '0x';
diff --git a/packages/extension-inject/src/types.ts b/packages/extension-inject/src/types.ts
index 0262eec8..3fc0302b 100644
--- a/packages/extension-inject/src/types.ts
+++ b/packages/extension-inject/src/types.ts
@@ -66,6 +66,7 @@ export interface MetadataDef extends MetadataDefBase {
   tokenSymbol: string;
   types: Record<string, Record<string, string> | string>;
   metaCalls?: string;
+  rawMetadata?: HexString;
   userExtensions?: ExtDef;
 }
 
diff --git a/packages/extension-ui/package.json b/packages/extension-ui/package.json
index 08a53879..09c16d2c 100644
--- a/packages/extension-ui/package.json
+++ b/packages/extension-ui/package.json
@@ -23,6 +23,7 @@
     "@fortawesome/free-solid-svg-icons": "^6.5.1",
     "@fortawesome/react-fontawesome": "^0.2.0",
     "@paraspell/xcm-analyser": "^1.3.0",
+    "@polkadot-api/merkleize-metadata": "^1.1.0",
     "@polkadot/api": "^12.2.1",
     "@polkadot/extension-base": "0.49.4-0-x",
     "@polkadot/extension-chains": "0.49.4-0-x",
diff --git a/packages/extension-ui/src/Popup/Metadata/Request.tsx b/packages/extension-ui/src/Popup/Metadata/Request.tsx
index 7079eaa6..eb29ac3f 100644
--- a/packages/extension-ui/src/Popup/Metadata/Request.tsx
+++ b/packages/extension-ui/src/Popup/Metadata/Request.tsx
@@ -70,7 +70,7 @@ function Request ({ className, metaId, request, url }: Props): React.ReactElemen
       </Table>
       <div className='requestInfo'>
         <Warning className='requestWarning'>
-          {t('This approval will add the metadata to your extension instance, allowing future requests to be decoded using this metadata.')}
+          {t('This approval will add the metadata to your extension instance, allowing future requests to be decoded using this metadata. It will also allow the use of Ledger\'s Generic Polkadot App.')}
         </Warning>
         <Button
           className='btnAccept'
diff --git a/packages/extension-ui/src/Popup/Signing/LedgerSign.tsx b/packages/extension-ui/src/Popup/Signing/LedgerSign.tsx
index 540e54ab..6322143a 100644
--- a/packages/extension-ui/src/Popup/Signing/LedgerSign.tsx
+++ b/packages/extension-ui/src/Popup/Signing/LedgerSign.tsx
@@ -1,15 +1,19 @@
 // Copyright 2019-2024 @polkadot/extension-ui authors & contributors
 // SPDX-License-Identifier: Apache-2.0
 
-import type { ExtrinsicPayload } from '@polkadot/types/interfaces';
+import type { Chain } from '@polkadot/extension-chains/types';
+import type { SignerPayloadJSON } from '@polkadot/types/types';
 import type { HexString } from '@polkadot/util/types';
 
 import { faSync } from '@fortawesome/free-solid-svg-icons';
 import { FontAwesomeIcon } from '@fortawesome/react-fontawesome';
 import React, { useCallback, useEffect, useState } from 'react';
 
+import { assert, objectSpread, u8aToHex } from '@polkadot/util';
+import { merkleizeMetadata } from '@polkadot-api/merkleize-metadata';
+
 import { Button, Warning } from '../../components/index.js';
-import { useLedger, useTranslation } from '../../hooks/index.js';
+import { useLedger, useMetadata, useTranslation } from '../../hooks/index.js';
 import { styled } from '../../styled.js';
 
 interface Props {
@@ -18,21 +22,44 @@ interface Props {
   className?: string;
   error: string | null;
   genesisHash?: string;
-  onSignature?: ({ signature }: { signature: HexString }) => void;
-  payload?: ExtrinsicPayload;
+  onSignature?: ({ signature }: { signature: HexString }, signedTransaction: HexString) => void;
+  payload?: SignerPayloadJSON;
   setError: (value: string | null) => void;
 }
 
+function getMetadataProof (chain: Chain, payload: SignerPayloadJSON) {
+  const m = chain.definition.rawMetadata;
+
+  assert(m, 'To sign with Ledger\'s Polkadot Generic App, the metadata must be present in the extension.');
+
+  const merkleizedMetadata = merkleizeMetadata(m, {
+    base58Prefix: chain.ss58Format,
+    decimals: chain.tokenDecimals,
+    specName: chain.name.toLowerCase(),
+    specVersion: chain.specVersion,
+    tokenSymbol: chain.tokenSymbol
+  });
+  const metadataHash = u8aToHex(merkleizedMetadata.digest());
+  const newPayload = objectSpread<SignerPayloadJSON>({}, payload, { metadataHash, mode: 1 });
+  const raw = chain.registry.createType('ExtrinsicPayload', newPayload);
+
+  return {
+    raw,
+    txMetadata: merkleizedMetadata.getProofForExtrinsicPayload(u8aToHex(raw.toU8a(true)))
+  };
+}
+
 function LedgerSign ({ accountIndex, addressOffset, className, error, genesisHash, onSignature, payload, setError }: Props): React.ReactElement<Props> {
   const [isBusy, setIsBusy] = useState(false);
   const { t } = useTranslation();
+  const chain = useMetadata(genesisHash);
   const { error: ledgerError, isLoading: ledgerLoading, isLocked: ledgerLocked, ledger, refresh, warning: ledgerWarning } = useLedger(genesisHash, accountIndex, addressOffset);
 
   useEffect(() => {
     if (ledgerError) {
       setError(ledgerError);
     }
-  }, [ledgerError, setError]);
+  }, [chain, ledgerError, setError]);
 
   const _onRefresh = useCallback(() => {
     refresh();
@@ -41,21 +68,43 @@ function LedgerSign ({ accountIndex, addressOffset, className, error, genesisHas
 
   const _onSignLedger = useCallback(
     (): void => {
-      if (!ledger || !payload || !onSignature) {
+      if (!ledger || !payload || !onSignature || !chain) {
         return;
       }
 
+      if (!chain?.definition.rawMetadata) {
+        setError('No metadata found for this chain. You must upload the metadata to the extension in order to use Ledger.');
+      }
+
+      const { raw, txMetadata } = getMetadataProof(chain, payload);
+
+      const metaBuff = Buffer.from(txMetadata);
+
       setError(null);
       setIsBusy(true);
-      ledger.sign(payload.toU8a(true), accountIndex, addressOffset)
+      ledger.signWithMetadata(raw.toU8a(true), accountIndex, addressOffset, { metadata: metaBuff })
         .then((signature) => {
-          onSignature(signature);
+          const extrinsic = chain.registry.createType(
+            'Extrinsic',
+            { method: raw.method },
+            { version: 4 }
+          );
+
+          ledger.getAddress(chain.ss58Format, false, accountIndex, addressOffset)
+            .then(({ address }) => {
+              extrinsic.addSignature(address, signature.signature, raw.toHex());
+              onSignature(signature, extrinsic.toHex());
+            })
+            .catch((e: Error) => {
+              setError(e.message);
+              setIsBusy(false);
+            });
         }).catch((e: Error) => {
           setError(e.message);
           setIsBusy(false);
         });
     },
-    [accountIndex, addressOffset, ledger, onSignature, payload, setError]
+    [accountIndex, addressOffset, chain, ledger, onSignature, payload, setError]
   );
 
   return (
@@ -93,7 +142,7 @@ function LedgerSign ({ accountIndex, addressOffset, className, error, genesisHas
   );
 }
 
-export default styled(LedgerSign)<Props>`
+export default styled(LedgerSign) <Props>`
   flex-direction: column;
   padding: 6px 24px;
 
diff --git a/packages/extension-ui/src/Popup/Signing/Request/index.tsx b/packages/extension-ui/src/Popup/Signing/Request/index.tsx
index 4a5d40a6..8a835d63 100644
--- a/packages/extension-ui/src/Popup/Signing/Request/index.tsx
+++ b/packages/extension-ui/src/Popup/Signing/Request/index.tsx
@@ -68,8 +68,8 @@ export default function Request ({ account: { accountIndex, addressOffset, genes
   }, [request]);
 
   const _onSignature = useCallback(
-    ({ signature }: { signature: HexString }): void => {
-      approveSignSignature(signId, signature)
+    ({ signature }: { signature: HexString }, signedTransaction?: HexString): void => {
+      approveSignSignature(signId, signature, signedTransaction)
         .then(() => onAction())
         .catch((error: Error): void => {
           setError(error.message);
@@ -117,7 +117,7 @@ export default function Request ({ account: { accountIndex, addressOffset, genes
             error={error}
             genesisHash={json.genesisHash}
             onSignature={_onSignature}
-            payload={payload}
+            payload={json}
             setError={setError}
           />
         )}
diff --git a/packages/extension-ui/src/hooks/useLedger.ts b/packages/extension-ui/src/hooks/useLedger.ts
index dca2c2af..b645f3f1 100644
--- a/packages/extension-ui/src/hooks/useLedger.ts
+++ b/packages/extension-ui/src/hooks/useLedger.ts
@@ -6,13 +6,16 @@
 /* eslint-disable deprecation/deprecation */
 
 import type { Network } from '@polkadot/networks/types';
+import type { HexString } from '@polkadot/util/types';
 
 import { useCallback, useEffect, useMemo, useState } from 'react';
 
-import { Ledger } from '@polkadot/hw-ledger';
+import { LedgerGeneric } from '@polkadot/hw-ledger';
+import { knownLedger } from '@polkadot/networks/defaults';
 import { settings } from '@polkadot/ui-settings';
 import { assert } from '@polkadot/util';
 
+import chains from '../../../extension-ui/src/util/chains';
 import ledgerChains from '../util/legerChains.js';
 import useTranslation from './useTranslation.js';
 
@@ -26,7 +29,7 @@ interface State extends StateBase {
   error: string | null;
   isLoading: boolean;
   isLocked: boolean;
-  ledger: Ledger | null;
+  ledger: LedgerGeneric | null;
   refresh: () => void;
   warning: string | null;
 }
@@ -44,8 +47,8 @@ function getState (): StateBase {
   };
 }
 
-function retrieveLedger (genesis: string): Ledger {
-  let ledger: Ledger | null = null;
+function retrieveLedger (genesis: string): LedgerGeneric {
+  let ledger: LedgerGeneric | null = null;
 
   const { isLedgerCapable } = getState();
 
@@ -55,7 +58,11 @@ function retrieveLedger (genesis: string): Ledger {
 
   assert(def, 'There is no known Ledger app available for this chain');
 
-  ledger = new Ledger('webusb', def.network);
+  assert(def.slip44, 'Slip44 is not available for this network, please report an issue to update this chains slip44');
+
+  // All chains use the `slip44` from polkadot in their derivation path in ledger.
+  // This interface is specific to the underlying PolkadotGenericApp.
+  ledger = new LedgerGeneric('webusb', def.network, knownLedger['polkadot']);
 
   return ledger;
 }
@@ -68,6 +75,7 @@ export default function useLedger (genesis?: string | null, accountIndex = 0, ad
   const [error, setError] = useState<string | null>(null);
   const [address, setAddress] = useState<string | null>(null);
   const { t } = useTranslation();
+
   const ledger = useMemo(() => {
     setError(null);
     setIsLocked(false);
@@ -102,7 +110,15 @@ export default function useLedger (genesis?: string | null, accountIndex = 0, ad
     setError(null);
     setWarning(null);
 
-    ledger.getAddress(false, accountIndex, addressOffset)
+    // This is used with a genesisHash only when importing the Ledger account
+    // and when signing with Ledger. In both cases, the genesisHash is known and
+    // will be in this array.
+    const chosenNetwork = chains.find(({ genesisHash }) => genesisHash === genesis as HexString);
+
+    // Just in case, but this shouldn't be triggered
+    assert(chosenNetwork, t('This network is not available, please report an issue to update the known chains'));
+
+    ledger.getAddress(chosenNetwork.ss58Format, false, accountIndex, addressOffset)
       .then((res) => {
         setIsLoading(false);
         setAddress(res.address);
diff --git a/packages/extension-ui/src/messaging.ts b/packages/extension-ui/src/messaging.ts
index 2871766b..c3df1089 100644
--- a/packages/extension-ui/src/messaging.ts
+++ b/packages/extension-ui/src/messaging.ts
@@ -118,8 +118,8 @@ export async function approveSignPassword (id: string, savePass: boolean, passwo
   return sendMessage('pri(signing.approve.password)', { id, password, savePass });
 }
 
-export async function approveSignSignature (id: string, signature: HexString): Promise<boolean> {
-  return sendMessage('pri(signing.approve.signature)', { id, signature });
+export async function approveSignSignature (id: string, signature: HexString, signedTransaction?: HexString): Promise<boolean> {
+  return sendMessage('pri(signing.approve.signature)', { id, signature, signedTransaction });
 }
 
 export async function createAccountExternal (name: string, address: string, genesisHash: HexString | null): Promise<boolean> {
diff --git a/packages/extension/public/locales/en/translation.json b/packages/extension/public/locales/en/translation.json
index ae92ceca..87fb67cd 100644
--- a/packages/extension/public/locales/en/translation.json
+++ b/packages/extension/public/locales/en/translation.json
@@ -68,7 +68,6 @@
   "decimals": "",
   "symbol": "",
   "upgrade": "",
-  "This approval will add the metadata to your extension instance, allowing future requests to be decoded using this metadata.": "",
   "Yes, do this metadata update": "",
   "Reject": "",
   "Restore from JSON": "",
@@ -176,5 +175,8 @@
   "Is your ledger locked?": "",
   "App \"{{network}}\" does not seem to be open": "",
   "Ledger error: {{errorMessage}}": "",
-  "assetId": ""
+  "assetId": "",
+  "This approval will add the metadata to your extension instance, allowing future requests to be decoded using this metadata. It will also allow the use of Ledger's Generic Polkadot App.": "",
+  "No metadata found for this chain. You must upload the metadata to the extension in order to use Ledger.": "",
+  "This network is not available, please report an issue to update the known chains": ""
 }
diff --git a/yarn.lock b/yarn.lock
index 63e8ffa3..c2db0294 100644
--- a/yarn.lock
+++ b/yarn.lock
@@ -668,6 +668,16 @@ __metadata:
   languageName: node
   linkType: hard
 
+"@polkadot-api/merkleize-metadata@npm:^1.1.0":
+  version: 1.1.1
+  resolution: "@polkadot-api/merkleize-metadata@npm:1.1.1"
+  dependencies:
+    "@polkadot-api/substrate-bindings": "npm:0.6.1"
+    "@polkadot-api/utils": "npm:0.1.1"
+  checksum: 10/dc0d1aa9e15049fdf263451ea1a8d7a4c5c5907e8b9b7ac8861f2e3281a82e99b5b07619a2c5cab105d8c14253007a006a7bc9d44fcaef1eb1d0356fc63d0485
+  languageName: node
+  linkType: hard
+
 "@polkadot-api/metadata-builders@npm:0.0.1":
   version: 0.0.1
   resolution: "@polkadot-api/metadata-builders@npm:0.0.1"
@@ -704,6 +714,18 @@ __metadata:
   languageName: node
   linkType: hard
 
+"@polkadot-api/substrate-bindings@npm:0.6.1":
+  version: 0.6.1
+  resolution: "@polkadot-api/substrate-bindings@npm:0.6.1"
+  dependencies:
+    "@noble/hashes": "npm:^1.3.1"
+    "@polkadot-api/utils": "npm:0.1.1"
+    "@scure/base": "npm:^1.1.1"
+    scale-ts: "npm:^1.6.0"
+  checksum: 10/bce8bd7758174302b9e72da1addce04103ab0e9d0626ff2eacffdfb28c7a058071edaf4b47a7569bd7c8c73dd1595e1d78f90d419abafb86a6eadf078c83d1e4
+  languageName: node
+  linkType: hard
+
 "@polkadot-api/substrate-client@npm:0.0.1":
   version: 0.0.1
   resolution: "@polkadot-api/substrate-client@npm:0.0.1"
@@ -718,6 +740,13 @@ __metadata:
   languageName: node
   linkType: hard
 
+"@polkadot-api/utils@npm:0.1.1":
+  version: 0.1.1
+  resolution: "@polkadot-api/utils@npm:0.1.1"
+  checksum: 10/ffd30039cd91396abb5528132bea9a72465eae9cdd088ecbd463ce962aa51c01b9e8c7d3e64c16c8438c0e55966c4d36fe4d18744a01b2b61f7e778f61dbf2b0
+  languageName: node
+  linkType: hard
+
 "@polkadot/api-augment@npm:12.2.1":
   version: 12.2.1
   resolution: "@polkadot/api-augment@npm:12.2.1"
@@ -996,6 +1025,7 @@ __metadata:
     "@fortawesome/free-solid-svg-icons": "npm:^6.5.1"
     "@fortawesome/react-fontawesome": "npm:^0.2.0"
     "@paraspell/xcm-analyser": "npm:^1.3.0"
+    "@polkadot-api/merkleize-metadata": "npm:^1.1.0"
     "@polkadot/api": "npm:^12.2.1"
     "@polkadot/dev-test": "npm:^0.79.3"
     "@polkadot/extension-base": "npm:0.49.4-0-x"